Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR

AL Okello; L Thomas; P Inthavong; A Ash; B Khamlome; C Keokamphet; K Newberry; CG Gauci; S Gabriël; P Dorny; RCA Thompson; MW Lightowlers; J Allen

Journal article

Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR

AL Okello, L Thomas, P Inthavong, A Ash, B Khamlome, C Keokamphet, K Newberry, CG Gauci, S Gabriël, P Dorny, RCA Thompson, MW Lightowlers, J Allen

Acta Tropica | ELSEVIER | Published : 2016

DOI: 10.1016/j.actatropica.2016.03.012

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Abstract

Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400 mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30 mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-anti..

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University of Melbourne Researchers

Charles Gauci Author

Marshall Lightowlers Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The SPSP human and animal health component wish to thank their project counterparts from the Centre for International Agriculture in the Tropics (CIAT) and the Lao PDR National Agricultural and Forestry Research Institute (NAFRI) for their assistance during the pig interventions. The team also wish to thank the Lao PDR national WHO office for their overall support, as well as the Lao PDR Department for Communicable Disease Control (DCDC) for their facilitation and assistance in the human MDA interventions. In particular, the project team would like to thank the staff from the provincial and district Ministry of Health offices for their care and support in building community rapport during the project lifetime, and finally the community themselves for their hospitality, cooperation and trust. This research was funded by the Australian Centre for International Agricultural Research (ACIAR) Animal Health Programme, grant number AH2009/001-019. Funding support is also acknowledged from the Australian National Health and Medical Research Council, grants 1003546 and 1043327 (MWL).